I've used AVG for as long as I can remember. I recommend it to anybody who asks about anti-virus software. People install so much useless crap on their computer that slows it down. Anti-virus, spyware, etc, etc...
I run AVG, windows firewall, and sitting behind a secure router. I havent had a virus since the 90's, and I'm spyware free. I run adware about once a month, rarely finds anything.
Here's my recommendation. Dump Internet Explorer, and get Mozilla Firefox, say goodbye to annoying popups, better security, and no spyware. Tons of add-ons and plugins. Customized to your liking and you'll never look back at IE.