Rodger and Bill both have Gen 1 STs, as do I. My mom was able to squeeze about 28 mpg out of Jade with mostly highway commutes, especially driving back from Wichita to Mexico Missouri, staying off the cruise control, and using the 87 octane performance tune driving 60-65 on average. She drives my truck like it's really delicate. When I drive, I can usually squeak about 20 to 22 out of her on the 87 perf tune. I haven't tried the 91 perf tune for long distances yet. If gas prices stay the way they are, I'll probably drive on 87 to Louisville.
I have a mileage tune, but I have hardly used it. It's for highway use only. It changes the shiftpoints, and tries to keep the cruise control from downshifting so much. On some hills, and this was in Kansas and Missouri, the cruise control would sometimes downshift from OD to 3rd, and the RPMs would shoot up and the ST would try to rocket up the hill and attempt to either hold speed or get back up to speed as soon as possible. As you would think, it eats gas mileage. Jade drives herself harder than I do...